Advances in pericardial effusion after hematopoietic stem cell transplantation in children
Pericardial effusion is a potentially life-threatening complication after hematopoietic stem cell transplantation(HSCT)in children.The incidence of pericardial effusion in children was 4.4%to 37.8%.The occurrence of pericardial effusion is related to many risk factors such as transplant-related thrombomicroangi-opathy,pretreatment drugs,graft-versus-host disease,graft type,immunosuppressant,infection and so on.The treatment of pericardial effusion lacks a unified protocol,mainly focus onsupportive treatment,etiologic treat-ment and pericardial puncture.This paper reviewed the risk factors and treatment of pericardial effusion after HSCT in recent years,and provided suggestions for improving the early identification,diagnosis and treatment of pericardial effusion after HSCT in children.