Analysis of risk factors for prognosis of bladder carcinoma in situ and construction of nomogram
Objective To explore the risk factors affecting the prognosis of patients with bladder carci-noma in situ(CIS),and to establish a nomogram to intuitively predict the prognosis of patients with bladder CIS.Methods The clinical data of 832 patients with bladder CIS were selected from the database of surveil-1ance,epidemiology and final results from 2010 to 2015.Univariate and multivariate Cox proportional hazard models were used to analyze the independent risk factors affecting tumor-specific survival and overall survival in patients with bladder CIS.The nomogram was drawn by R language to visualize the survival model.Finally,the accuracy of the model was verified by consistency index and calibration curve.Results The independent risk factors affecting the tumor-specific survival of patients with bladder CIS included age and tumor grade(P＜0.05).The independent risk factors affecting the overall survival of patients with bladder CIS include age,tumor grade,and number of primary tumors(P＜0.05).The consistency indexes of the two were 0.745 and 0.709,respectively.Conclusion Age,tumor grade and number of primary tumors have important predic-tive value in the prognosis of patients with bladder CIS.The construction of nomogram can better make clini-cal decisions for patients with bladder CIS.
Bladder carcinoma in situPrognosisRisk factorsNomogram
万方数据
维普
