Clinical study of selective arterial infusion chemoembolization combined with systemic chemotherapy in patients with advanced esophageal cancer
Objective To evaluate the long-term efficacy and safety of selective arterial perfusion che-moembolization technique(SAPCT)combined with systemic chemotherapy(SC)in the treatment of advanced esophageal cancer.Methods A total of 112 patients with advanced esophageal cancer admitted to this hospital from June 2017 to June 2019 were divided into the experimental group(57 cases)and the control group(55 cases).The experimental group was given SAPCT combined with SC(5-fluorouracil/cisplatin),while the con-trol group was given SC(5-fluorouracil/cisplatin).All patients in the two groups received two cycles of chem-otherapy.The short-term and long-term clinical efficacy and the occurrence of adverse reactions were com-pared between the two groups.Results After one cycle of chemotherapy,the relief of dysphagia in the experi-mental group was significantly better than that in the control group(P＜0.05).After two cycles of chemo-therapy,there were statistically significant differences in partial remission rate and progression rate between the two groups(P＜0.05).The long-term curative effects of PFS and OS in the experimental group were better than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion SAPCT com-bined with SC in the treatment of advanced esophageal cancer can not only significantly relieve dysphagia symp-toms,but also significantly improve the prognosis of patients.
Esophageal cancerSelective arterial embolizationChemotherapyCombination therapyDysphagiaLater period
万方数据
维普
