Comparison of the efficacy of mini-incision and transcatheter aortic valve replacement under closed extracorporeal circulation in the treatment of aortic valvular lesion
Objective To compare and analyze the effects of mini-incision aortic valve replacement(MIS-AVR)and transcatheter aortic valve replacement(TAVR)under closed extracorporeal circulation on patients with aortic valvular lesion.Methods A total of 108 patients with aortic valvular lesion who accepted therapy in the hospital from May 2021 to June 2022 were selected and divided into the TAVR group(n=54,TAVR treatment)and the MIS-AVR group(n=54,MIS-AVR treatment)according to the type of surgery.The clinical potency,perioperative indicators,inflammatory factor standards,cardiac ability targets and com-plications of the two groups were compared.Results The total effective rate of the MIS-AVR group was 98.15％(53/54),compared with 96.30％(52/54)in the TAVR group,the difference was not statistically sig-nificant(P＞0.05).The slash size,surgery time,intraoperative blood transfusion and length of stay at hospi-tal in the MIS-AVR group were significantly higher than those in the TAVR group,and the differences were statistically significant(P＜0.05).After treatment,the levels of intercellular adhesion molecule-1,monocyte chemoattractant protein-1,long-term pentraxin-3,left ventricular diameter,pulmonary artery systolic pres-sure,interventricular septum thickness and mitral annulus velocity in the two groups were significantly lower than those before treatment,and the MIS-AVR group were less than those in the TAVR group,and the differ-ences were statistically significant(P＜0.05).The incidence of complications in the MIS-AVR group was 5.55％(3/54),and there was no significant difference compared with 9.25％(5/54)in the TAVR group(P＞0.05).Conclusion MIS-AVR and TAVR are both effective in the treatment of aortic valvular lesion.TAVR is easy to operate and has less trauma to perioperative sicks.However,MIS-AVR has better improve-ment in inflammatory factors and cardiac function,and the syndromes are slightly lower.
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