首页|地塞米松联合快速康复训练对全膝关节置换术后功能及镇痛的影响研究

地塞米松联合快速康复训练对全膝关节置换术后功能及镇痛的影响研究

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目的 探讨快速康复训练联合地塞米松对全膝关节置换(TKA)术后患者膝关节功能及镇痛等影响。方法 纳入2021年6月至2022年6月该院收治的64例TKA患者,根据其入院顺序随机分配至研究组(32例)和对照组(32例)。对照组患者术后仅采用快速康复训练,而研究组患者在快速康复训练基础上额外增加地塞米松磷酸钠注射液静脉滴注,比较2组患者各个随访时间点膝关节功能(KSS)评分、膝关节活动度(ROM)、疼痛视觉模拟评分法(VAS)评分及发生恶心呕吐反应的差异。结果 研究组患者术后膝关节功能KSS评分、膝关节ROM均明显高于对照组,而恶心呕吐反应发生率、术后前3 d时VAS评分均明显低于对照组,差异均有统计学意义(P<0。05);2组患者术后14 d时VAS评分比较,差异无统计学意义(P>0。05)。结论 围手术期给予地塞米松联合快速康复训练可明显提高患者TKA术后膝关节功能,且地塞米松对术后早期镇痛、止吐有明显优势。
Effect study of dexamethasone combined with rapid rehabilitation training on function and analgesia after total knee arthroplasty
Objective To explore the effect of rapid rehabilitation training combined with dexametha-sone on knee joint function and analgesia after total knee arthroplasty(TKA).Methods A total of 64 patients with TKA in the hospital from June 2021 to June 2022 were prospectively selected and randomly divided into the study group(n=32)and the control group(n=32).The control group only received rapid rehabilitation training,while the study group received intravenous drip of dexamethasone sodium phosphate injection on the basis of rapid rehabilitation training.The differences of knee joint function(KSS)score,knee joint range of motion(ROM),pain visual simulation(VAS)score and nausea and vomiting reaction were compared between the two groups at each follow-up time.Results The KSS score and ROM of knee joint in the study group were significantly higher than those in the control group,while the nausea and vomiting reaction and the VAS score in the first 3 days after operation were significantly lower than those in the control group,with statistical significance(P<0.05).There was no significant difference in VAS scores between the two groups at 14th postoperative day(P>0.05).Conclusion Perioperative dexamethasone combined with rapid rehabilitation training can significantly improve the knee function of patients after TKA,and dexamethasone has obvious ad-vantages in early postoperative analgesia and antiemesis.

DexamethasoneRapid rehabilitation trainingTotal knee arthroplastyGlucocorti-coidPerioperativeFunctionAnalgesia

益小平、韦继刚

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中国人民解放军陆军第九五八医院/西南医院江北院区骨科,重庆 400023

地塞米松 快速康复训练 全膝关节置换 糖皮质激素 围手术期 功能 镇痛

2024

现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
年,卷(期):2024.40(5)
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