首页|中医"治未病"理论防治结直肠息肉术后复发及改善临床症状的meta分析

中医"治未病"理论防治结直肠息肉术后复发及改善临床症状的meta分析

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目的 系统评价中医"治未病"理论指导下辨证论治使用中药或传统中医特色疗法防治结直肠息肉术后复发及改善临床症状的效果,为临床治疗此病提供更多方法。方法 选取中国知网、万方、中国维普、PubMed数据库进行计算机检索,筛选出在中医"治未病"理论指导下使用中药防治结直肠息肉术后复发的所有随机对照试验,共纳入15篇文献1 768例患者,其中对照组886例(在术后常规治疗上加用或不加用西药治疗),治疗组882例(在对照组基础上用中医或中药口服或外治干预)。采用RevMan5。4。1软件进行meta分析。结果 治疗组患者术后半年、1年、2年复发率,相关临床症状(腹痛、腹泻、便血)改善情况优于对照组,差异均有统计学意义(P<0。000 01),敏感性分析(术后1年)提示结果较稳定,具有可靠性。结论 中医"治未病"理论指导下的中医药干预对降低结直肠息肉术后复发率、改善临床症状有较好的效果。
Prevention and treatment of postoperative recurrence of colorectal polyps after operation and improvement of clinical symptoms based on the theory of'preventive treatment of disease'in traditional Chinese medicine:A meta-analysis
Objective To systematically evaluate the effect of traditional Chinese medicine or traditional Chinese medicine characteristic therapy on the prevention and treatment of postoperative recurrence of color-ectal polyps after operation and the improvement of clinical symptoms under the guidance of the theory of'preventive treatment of disease'in traditional Chinese medicine,so as to provide more methods for clinical treatment of this disease.Methods CNKI,Wanfang,VIP and PubMed database were selected for computer retrieval,and all randomized controlled trials of using traditional Chinese medicine to prevent and treat postop-erative recurrence of colorectal polyps after operation under the guidance of the theory of'preventive treat-ment of disease'of traditional Chinese medicine were screened out.A total of 15 articles were included in 1 768 patients,including 886 patients in the control group(treated with or without western medicine after routine treatment),and 882 patients in the treatment group(treated with traditional Chinese medicine or oral or ex-ternal treatment of traditional Chinese medicine on the basis of the control group).Meta-analysis was per-formed using RevMan 5.4.1 software.Results The recurrence rate and the improvement of related clinical symptoms(abdominal pain,diarrhea and hematochezia)in the treatment group were better than those in the control group at half a year,one year and two years after operation,and the differences were statistically sig-nificant(P<0.000 01).Sensitivity analysis(one year after operation)suggested that the results were stable and reliable.Conclusion The intervention of traditional Chinese medicine under the guidance of the theory of'preventive treatment of disease'of traditional Chinese medicine has a good effect on reducing the recurrence rate of colorectal polyps after operation and improving clinical symptoms.

Chinese medicine theoryPreventive treatment of diseaseColorectal polypsPostop-erative recurrenceClinical symptomsMeta-analysis

辜建萍、赖象权

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贵州中医药大学,贵州贵阳 550002

贵州中医药大学第一附属医院肛肠科,贵州贵阳 550001

中医理论 治未病 结直肠息肉 术后复发 临床症状 meta分析

2024

现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
年,卷(期):2024.40(5)
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