Prevention and treatment of postoperative recurrence of colorectal polyps after operation and improvement of clinical symptoms based on the theory of'preventive treatment of disease'in traditional Chinese medicine:A meta-analysis
Objective To systematically evaluate the effect of traditional Chinese medicine or traditional Chinese medicine characteristic therapy on the prevention and treatment of postoperative recurrence of color-ectal polyps after operation and the improvement of clinical symptoms under the guidance of the theory of'preventive treatment of disease'in traditional Chinese medicine,so as to provide more methods for clinical treatment of this disease.Methods CNKI,Wanfang,VIP and PubMed database were selected for computer retrieval,and all randomized controlled trials of using traditional Chinese medicine to prevent and treat postop-erative recurrence of colorectal polyps after operation under the guidance of the theory of'preventive treat-ment of disease'of traditional Chinese medicine were screened out.A total of 15 articles were included in 1 768 patients,including 886 patients in the control group(treated with or without western medicine after routine treatment),and 882 patients in the treatment group(treated with traditional Chinese medicine or oral or ex-ternal treatment of traditional Chinese medicine on the basis of the control group).Meta-analysis was per-formed using RevMan 5.4.1 software.Results The recurrence rate and the improvement of related clinical symptoms(abdominal pain,diarrhea and hematochezia)in the treatment group were better than those in the control group at half a year,one year and two years after operation,and the differences were statistically sig-nificant(P<0.000 01).Sensitivity analysis(one year after operation)suggested that the results were stable and reliable.Conclusion The intervention of traditional Chinese medicine under the guidance of the theory of'preventive treatment of disease'of traditional Chinese medicine has a good effect on reducing the recurrence rate of colorectal polyps after operation and improving clinical symptoms.
Chinese medicine theoryPreventive treatment of diseaseColorectal polypsPostop-erative recurrenceClinical symptomsMeta-analysis