首页|难治性SHPT患者行tPTX+AT术后复发的研究进展

难治性SHPT患者行tPTX+AT术后复发的研究进展

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继发性甲状旁腺功能亢进症(SHPT)是尿毒症患者进行长时间血液透析治疗过程中较为常见的并发症之一，SHPT患者经长时间的透析治疗最终发展为难治性SHPT，此时内科治疗效果较差甚至无效，手术治疗可使患者症状得到快速改善。目前，甲状旁腺全切除术联合自体移植术(tPTX+AT)是难治性SHPT患者主要的手术方式之一。然而近年来难治性SHPT患者行tPTX+AT后的康复管理问题日益突出，怎样降低其复发率是该领域研究的难点。该文对可能影响tPTX+AT术后复发的因素进行总结和讨论，为临床工作者进一步提高手术成功率，降低手术复发率，提高患者术后的生活质量，加强术后管理提供临床思路。
Research progress on recurrence after total parathyroidectomy combined with autologous transplantation surgery in patients with refractory secondary hyperparathyroidism
Secondary hyperparathyroidism(SHPT)is one of the most common complications in uremia patients undergoing long-term hemodialysis treatment.SHPT patients after long-term dialysis treatment e-ventually developed into refractory SHPT.At this time,the effect of medical treatment is poor or even ineffec-tive,and surgical treatment can make patients symptoms improve rapidly.At present,total parathyroidectomy+autologous transplantation(tPTX+AT)surgery is one of the main surgical methods for patients with re-fractory SHPT.However,in recent years,the rehabilitation management problem of patients with refractory SHPT after tPTX+AT surgery has become increasingly prominent,and how to reduce the recurrence rate is a difficult point in this field.This article summarizes and discusses the factors that may affect the recurrence af-ter tPTX+AT surgery,so as to provide clinical ideas for clinicians to further improve the success rate of sur-gery,reduce the recurrence rate of surgery,improve the quality of life of patients after surgery,and strengthen the postoperative management.

Secondary hyperparathyroidismMaintenance hemodialysisComplicationsTotal parathyroidectomyAutologous transplantationSurgical treatmentRecurrenceReview

卢东军、刘天奇

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右江民族医学院,广西百色 533000

广西壮族自治区人民医院,广西南宁 530021

广西壮族自治区江滨医院普通外科,广西 南宁 530021

继发性甲状旁腺功能亢进症 维持性血液透析 并发症 甲状旁腺全切除手术 自体移植术 手术治疗 复发 综述

广西壮族自治区卫健委医疗卫生适宜技术开发与推广应用项目

S2017083

2024

10.3969/j.issn.1009-5519.2024.05.027

现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子：0.758
ISSN：1009-5519
年,卷(期)：2024.40(5)
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