现代医药卫生2024,Vol.40Issue(5) :849-853.DOI:10.3969/j.issn.1009-5519.2024.05.028

基于组学技术的针灸治疗膝骨关节炎的研究进展

Research progress in the treatment of knee osteoarthritis with acupuncture and moxibustion based on omics technology

张峰 周若涵 朱翔宇 王晓彤
现代医药卫生2024,Vol.40Issue(5) :849-853.DOI:10.3969/j.issn.1009-5519.2024.05.028

基于组学技术的针灸治疗膝骨关节炎的研究进展

Research progress in the treatment of knee osteoarthritis with acupuncture and moxibustion based on omics technology

张峰 1周若涵 1朱翔宇 1王晓彤1
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作者信息

  • 1. 北京中医药大学针灸推拿学院,北京 102401
  • 折叠

摘要

膝骨关节炎(KOA)是一种好发于中老年人中的膝关节软骨退行性病变.针灸治疗KOA疗效确切,其效应机制较为复杂.组学技术揭示生物体不同组分相互作用和动态变化.组学技术的应用和发展为针灸治疗KOA的效应机制提供新的视野.因此,该文分别综述了基因组学、转录组学、蛋白质组学、代谢组学技术在针灸治疗KOA中的应用,以期从单一组学和多组学层面深入了解针灸治疗KOA的作用机制.

Abstract

Knee osteoarthritis(KOA)is a degenerative disease of the knee joint cartilage that is more common in middle-aged and elderly people.Acupuncture and moxibustion has a definite therapeutic effect on KOA,and its mechanism is complex.Omics techniques reveals the interaction and dynamic changes of differ-ent components in organisms.The application and development of omics technology provide a new perspective for the effect mechanism of acupuncture and moxibustion on KOA.Therefore,this article reviewes the appli-cation of genomics,transcriptomics,proteomics,and metabolomics in the treatment of KOA with acupuncture and moxibustion,in order to deeply understand the mechanism of acupuncture and moxibustion in the treat-ment of KOA from the perspective of monomics and multimics.

关键词

针灸/膝骨关节炎/组学技术/中药治疗/综述

Key words

Acupuncture and moxibustion/Knee osteoarthritis/Omics techniques/Traditional Chinese medicine treatment/Review

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基金项目

国家中医药管理局高水平针灸学重点学科项目(zyyzdxk-2023254)

四川省科技厅苗子工程重点项目(2021JDRC0149)

北京中医药大学2022年度基本科研业务费揭榜挂帅项目(2022-JYB-JYBZ-027)

出版年

2024
现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
参考文献量31
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