Knee osteoarthritis(KOA)is a degenerative disease of the knee joint cartilage that is more common in middle-aged and elderly people.Acupuncture and moxibustion has a definite therapeutic effect on KOA,and its mechanism is complex.Omics techniques reveals the interaction and dynamic changes of differ-ent components in organisms.The application and development of omics technology provide a new perspective for the effect mechanism of acupuncture and moxibustion on KOA.Therefore,this article reviewes the appli-cation of genomics,transcriptomics,proteomics,and metabolomics in the treatment of KOA with acupuncture and moxibustion,in order to deeply understand the mechanism of acupuncture and moxibustion in the treat-ment of KOA from the perspective of monomics and multimics.
关键词
针灸/膝骨关节炎/组学技术/中药治疗/综述
Key words
Acupuncture and moxibustion/Knee osteoarthritis/Omics techniques/Traditional Chinese medicine treatment/Review