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结核病病毒载体疫苗研究进展

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结核病(TB)由结核分枝杆菌感染引起,其发病率和死亡率在传染性疾病中均居于前列,而疫苗是有效控制TB的重要因素.鉴于卡介苗(BCG)对成年人TB预防效果有限,新型TB疫苗(尤其是病毒载体疫苗)意义重大.该文拟对TB病毒载体疫苗的类型、效力及其研究进展做一综述.
Research progress on vector vaccine of tuberculosis virus
Tuberculosis(TB)is caused by the infection of Mycobacterium tuberculosis,and its morbidi-ty and mortality are among the highest among infectious diseases.Vaccines are an important factor in the ef-fective control of TB.In view of the limited preventive effect of BCG on TB in adults,new TB vaccines(espe-cially viral vector vaccines)are of great significance.This article aimed to provide a review of the types,effica-cy and research progress of TB virus vector vaccine.

TuberculosisBCG vaccineViral vector vaccineReview

杨骏昊、杨雅婷、王晓春

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安徽理工大学病原微生物实验室,安徽淮南 232001

结核病 卡介苗 病毒载体疫苗 综述

大学生创新创业训练计划

S202310361255

2024

现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
年,卷(期):2024.40(6)
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