Research progress on the relationship between periodontitis and liver disease
As the beginning of the digestive tract,the mouth has a natural connection with the intes-tines and the liver.Oral diseases are also closely related to liver diseases.Periodontitis is the most common o-ral disease and its periodontal bacterial lesions often influence the prognosis and progression of liver disease through direct anatomical invasion and the oral-gut-liver axis.Periodontal bacteria can also affect the liver through damaged intestinal epithelium circulating through the portal vein.This article provided a systematic review of periodontitis,the oral-intestinal-hepatic axis,and liver disease.