首页|硬膜外分娩镇痛的实施时长对中转剖宫产时硬膜外麻醉效果影响的研究

硬膜外分娩镇痛的实施时长对中转剖宫产时硬膜外麻醉效果影响的研究

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目的 探讨硬膜外分娩镇痛的实施时长对中转剖宫产时硬膜外麻醉效果的影响。方法 采用前瞻性队列研究,收集2020年1月至2021年6月于新疆维吾尔 自治区乌鲁木齐市妇幼保健院产房内实施硬膜外分娩镇痛后中转剖宫产产妇的临床资料,依据分娩镇痛的实施时长8 h为分界值,<8 h为短时组,>8 h为长时组,中转剖宫产时均通过分娩镇痛时置入的硬膜外导管给药,常规首先给予1。5%的利多卡因3 mL为试验剂量,起效后,给予1%利多卡因+0。75%罗哌卡因混合液10~15 mL进行硬膜外麻醉,比较两组产妇硬膜外麻醉效果和失败率。结果 共纳入56例产妇,其中短时组26例,长时组30例,长时组5例硬膜外麻醉失败,失败率明显高于短时组(16。7%vs。0,P<0。05),短时组麻醉成功产妇分娩镇痛药液剂量明显少于长时组[(45。22±5。35)mL vs。(80。15±10。50)mL],差异均有统计学意义(P<0。05)。两组产妇剖宫产中的局部麻醉药用药总量[(15。18±2。52)mL vs。(14。38±1。05)mL]、给予用药剂量至切皮时间[(22。05±8。42)min vs。(23。45±6。87)min]、手术时间[(88。75±21。72)min vs。(85。10±13。22)min]比较,差异均无统计学意义(P>0。05)。两组均无产妇和新生儿不良事件发生。长时组麻醉后感觉阻滞平面[T9(T4,T10)vs。T6(T4,T7)]和运动阻滞分级[1(0,1)级vs。2(1,3)级]均低于短时组(P<0。05);长时组在切皮后分离肌肉时的不适主诉(24。0%vs。11。5%)和子宫缝合完毕探查腹腔时的不适主诉(84。0%vs。61。5%)均高于短时组,差异均有统计学意义(P<0。05)。结论 对于在产房接受硬膜外分娩镇痛的产妇而言,分娩镇痛实施时间越长,在后续的中转剖宫产过程中不仅会降低术中硬膜外的麻醉效果,还增加了麻醉失败的风险,增加再次穿刺的概率。
Study on the influence of the duration of epidural labor analgesia on the effect of epidural anesthesia during transition to cesarean section
Objective To explore the effect of the duration of epidural labor analgesia on the effect of epidural anesthesia during intrapartum cesarean section.Methods A prospective cohort study was conducted to collect and analyze the clinical data of women who were transferred to cesarean section after epidural labor analgesia in the delivery room of the Maternal and Child Health Hospital of Xinjiang Uygur Autonomous Re-gion from January 2020 to June 2022.According to the implementation time of labor analgesia the cut-off val-ue of 8 hours as the cut-off value,<8 hours as the short-term group,>8 hours as the long-term group.All of them were given drugs through epidural catheter inserted during labor analgesia during the transfer to cesare-an section.Routine first give 3 mL of 1.5%lidocaine as the experimental dose.After the onset of effect,10-15 mL of 1%lidocaine and 0.75%ropivacaine mixture was given for epidural anesthesia,and compare the effects and failure rate of epidural anesthesia between the two groups.Results A total of 56 parturients were included,including 26 in the short-term group and 30 in the long-term group.Five cases of epidural anesthesia failure in the long-term group.The failure rate of long-term group was significantly higher than that in the short-term group(16.7%vs.0),and the dosage of delivery analgesic solution of other parturients in the short-term group was significantly less than that in the long-term group[(45.22±5.35)mL vs.(80.15± 10.50)mL],the differences were statistically significant(P<0.05).There were no significant differences in the total amount of local anesthetic used in cesarean section in the two groups[(15.18±2.52)mL vs.(14.38±1.05)mL],the time from medication dose to skin incision[(22.05±8.42)min vs.(23.45±6.87)min].the operation time[(88.75±21.72)min vs.(85.10±13.22)min]between the two groups.There were no maternal and neonatal adverse events in the two groups.the sensory block level after anesthesia in the long-term group[T9(T4),T10)vs.T6(T4,T7)]and the grade of motor block[1(0,1)gradle class vs.2(1,3)gradle class]were lower than those in short-term group.Compared with the short-term group,the long-term group had significantly higher complaints of discomfort during muscle separation after skin incision(24.0%vs.11.5%)and abdominal exploration after uterine suture(84.0%vs.61.5%),the differences were statistically significant(P<0.05).Conclusion For the parturients who receive epidural labor analgesia in the delivery room,the longer the duration of labor analgesia,it will not only reduce the effect of epidural anesthesia,but also in-crease the risk of anesthesia failure and the probability of re-puncture during the subsequent cesarean section.

Epidural labor analgesiaCesarean sectionDurationEpidural anesthesia

玛荷芭·玉素甫江、林丽

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乌鲁木齐市妇幼保健院,新疆乌鲁木齐 830000

硬膜外分娩镇痛 实施时长 剖宫产 硬膜外麻醉

新疆维吾尔自治区自然科学基金

2019D01A19

2024

现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
年,卷(期):2024.40(7)
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