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卵巢癌患者围手术期营养状况现状调查与分析

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目的 分析卵巢癌患者术前术后营养状况。方法 选取2020年3月至2022年2月该院妇科收治的卵巢癌患者110例作为研究对象,测定所有患者术前和术后的血常规和生化指标,根据血清蛋白和淋巴细胞计数,计算预后营养指数(PNI)。结果 患者平均年龄为55。35岁,卵巢癌患者术前贫血所占百分比为27。27%,轻度贫血为24。55%,中度贫血为2。73%,低蛋白血症为10。00%,低血脂为2。73%,低钙血症为8。18%,低钾血症为4。55%,低钠血症为6。36%。卵巢癌患者术后贫血所占百分比为78。18%,轻度贫血为43。64%,中度贫血为34。55%;低蛋白血症为76。36%,轻度低蛋白血症为42。73%,中度低蛋白血症为16。36%,重度低蛋白血症为17。27%;低血脂为30。91%;低钙血症为64。55%;低钾血症为40。00%;低钠血症为40。91%。病理Ⅲ~Ⅳ期者术前贫血、低蛋白血症、低钠血症所占百分比均显著高于病理Ⅰ~Ⅱ期者,且差异均有统计学意义(P<0。05)。Pearson相关分析提示,PNI与术后血红蛋白、血清总蛋白、血清蛋白、总胆固醇、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、血钙呈正相关(r=0。491、0。557、0。395、0。273、0。442、0。389,P<0。001);与术后红细胞计数、空腹血糖、甘油三酯、血钠和血钙均无明显相关性(P>0。05)。结论 营养不良在卵巢癌患者中发生比例高,尤其是在术后卵巢癌患者中表现得更为明显。
Investigation and analysis of perioperative nutritional status of ovarian cancer patients
Objective To analyze the preoperative and postoperative nutritional status of patients with ovarian cancer.Methods A total of 110 ovarian cancer patients admitted to the Department of Gynecology in our hospital from March 2020 to February 2022 were selected as the study objects.The preoperative and post-operative blood routine and biochemistry of all patients were measured,and prognostic nutritional index(PNI)was calculated according to serum albumin and lymphocyte counts.Results The average age of the study pop-ulation was 55.35 years old.The proportion of preoperative anemia in ovarian cancer patients was 27.27%,the proportion of mild anemia was 24.55%,the proportion of moderate anemia was 2.73%,the proportion of hypoproteinemia was 10.00%,the proportion of hypolipidemia was 2.73%,the proportion of hypocalcemia was 8.18%,and the proportion of hypokalemia was 4.55%.The proportion of hyponatremia was 6.36%.The proportion of postoperative anemia in ovarian cancer patients was 78.18%,43.64%,34.55%,76.36%,42.73%,16.36%,and 17.27%,respectively.The proportion of hypolipidemia was 30.91%,hypocalcemia 64.55%,hypokalemia 40.00%and hyponatremia 40.91%.The proportion of anemia,hypoproteinemia and hy-ponatremia before surgery in patients with pathological stage Ⅲ to Ⅳ were significantly higher than those with pathological stage Ⅰ to Ⅱ,and the differences were statistically significant(P<0.05).Pearson correla-tion analysis suggested that PNI was correlated with postoperative hemoglobin,serum total protein,serum al-bumin,total cholesterol,low density lipoprotein cholesterol,high density lipoprotein cholesterol and blood cal-cium were correlated(r=0.491,0.557,0.395,0.273,0.442,0.389,P<0.001),and there was no significant correlation with postoperative red blood cell count,fasting blood glucose,triglyceride,blood sodium and blood calcium(P>0.05).Conclusion The incidence of malnutrition is high in ovarian cancer patients,especially in postoperative ovarian cancer patients.

NutritionOvarian cancerPrognostic nutritional index

江雨璐、刘丽丽、曹耀萍、戴菲菲、杨雯

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南京鼓楼医院妇科,江苏南京 210000

营养 卵巢癌 预后营养指数

国家卫生健康委医院管理研究所项目

YLZLXZ23G011

2024

现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
年,卷(期):2024.40(7)
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