Investigation and analysis of perioperative nutritional status of ovarian cancer patients
Objective To analyze the preoperative and postoperative nutritional status of patients with ovarian cancer.Methods A total of 110 ovarian cancer patients admitted to the Department of Gynecology in our hospital from March 2020 to February 2022 were selected as the study objects.The preoperative and post-operative blood routine and biochemistry of all patients were measured,and prognostic nutritional index(PNI)was calculated according to serum albumin and lymphocyte counts.Results The average age of the study pop-ulation was 55.35 years old.The proportion of preoperative anemia in ovarian cancer patients was 27.27%,the proportion of mild anemia was 24.55%,the proportion of moderate anemia was 2.73%,the proportion of hypoproteinemia was 10.00%,the proportion of hypolipidemia was 2.73%,the proportion of hypocalcemia was 8.18%,and the proportion of hypokalemia was 4.55%.The proportion of hyponatremia was 6.36%.The proportion of postoperative anemia in ovarian cancer patients was 78.18%,43.64%,34.55%,76.36%,42.73%,16.36%,and 17.27%,respectively.The proportion of hypolipidemia was 30.91%,hypocalcemia 64.55%,hypokalemia 40.00%and hyponatremia 40.91%.The proportion of anemia,hypoproteinemia and hy-ponatremia before surgery in patients with pathological stage Ⅲ to Ⅳ were significantly higher than those with pathological stage Ⅰ to Ⅱ,and the differences were statistically significant(P<0.05).Pearson correla-tion analysis suggested that PNI was correlated with postoperative hemoglobin,serum total protein,serum al-bumin,total cholesterol,low density lipoprotein cholesterol,high density lipoprotein cholesterol and blood cal-cium were correlated(r=0.491,0.557,0.395,0.273,0.442,0.389,P<0.001),and there was no significant correlation with postoperative red blood cell count,fasting blood glucose,triglyceride,blood sodium and blood calcium(P>0.05).Conclusion The incidence of malnutrition is high in ovarian cancer patients,especially in postoperative ovarian cancer patients.
NutritionOvarian cancerPrognostic nutritional index