Clinical status of percutaneous closure of patent foramen ovale in the treatment of migraine
A patent foramen ovale(PFO)is a cardiac anatomical abnormality that usually fails to close normally at birth,resulting in the blood flow channel between the left ventricle and the right ventricle still ex-isting.In recent years,a growing number of studies have shown that there is a correlation between PFO and migraine,especially in migraine patients with aura.With the continuous development of interventional tech-niques in cardiology,interventional closure has become an effective method for the treatment of PFO.Studies have shown that the closure of PFO by using a closure device can reduce the risks associated with patent fora-men ovale,such as stroke.More encouragingly,some studies have found that PFO closure may help reduce the frequency and severity of migraine attacks.Anxiety and depression are common mental complications in mi-graine patients.Percutaneous PFO closure has shown favorable results in alleviating migraine symptoms and improving psychological status and quality of life.This review will also discuss the safety and efficacy of PFO closure,as well as the mechanisms associated with migraine,in order to further explore the clinical advances in this field.Finally,this paper emphasize the necessity of screening and managing the mental health status of pa-tients,and expects that future research can provide more clear guidance for PFO closure in the treatment of migraine.
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