摘要
热休克蛋白70(HSP70)是应激状态或高温下能抑制细胞蛋白质变性或展开的蛋白质,在炎症因子表达、抑制细胞凋亡、抑制蛋白质聚集等方面发挥关键作用.该文阐述了国内外研究HSP70与肺癌、肺炎、肺结核、哮喘等肺部疾病发病机制的密切关系,为肺部疾病的快速诊断提供了新思路.
Abstract
Heat shock protein 70(HSP70)is a protein that can inhibit cell protein denaturation or ex-pansion under stress or high temperature.It plays a key role in the expression of inflammatory factors,inhibi-tion of apoptosis,and inhibition of protein aggregation.HSP70 is a protein that can inhibit cell protein denat-uration or expansion under stress or high temperature.It plays a key role in the expression of inflammatory factors,inhibition of apoptosis,and inhibition of protein aggregation.This paper expounds the close relation-ship between heat shock protein 70 and the pathogenesis of lung diseases such as lung cancer,pneumonia,pul-monary tuberculosis and asthma,and provides a new idea for the rapid diagnosis of lung diseases.
基金项目
贵州省卫生健康委科学技术基金(gzwjkj2020-1-062)
维普
万方数据