Application study of combined detection of PLT,MPV and BNP in patients with pulmonary heart disease
Objective To explore the application effect of combined detection of platelet count(PLT),mean platelet volume(MPV)and B-type natriuretic peptide(BNP)in patients with pulmonary heart disease.Methods A toatl of 180 patients hospitalized in the respiratory department of the hospital from March 2019 to April 2022 due to dyspnea were selected and divided into the non-pulmonary heart disease group(95 cases)and the pulmonary heart disease group(85 cases).Meanwhile,the pulmonary heart disease group was further divided into the acute exacerbation group(85 cases)and the remission group(85 cases)based on the treatment time.The changes in PLT,MPV,and BNP indicators among different groups were compared,and the correla-tion between BNP levels and MPV and PLT levels was analyzed.Results The PLT levels in the acute exacer-bation and remission groups were significantly lower than those in the non-pulmonary heart disease group,while the MPV and BNP levels were significantly higher than those in the non-pulmonary heart disease group,with statistically significant differences(P＜0.05).There were statistically significant differences in PLT,MPV and BNP levels between the acute exacerbation group and the remission group(P＜0.05).The levels of BNP[(332.24±37.10)μg/mL]and MPV[(11.92±1.26)fL]in the pulmonary heart disease group were significantly higher than those in the non-pulmonary heart disease group,while the levels of PLT[(142.25± 31.32)× 109/L]were significantly lower than those in the non-pulmonary heart disease group,and the differ-ences were statistically significant(P＜0.05).After excluding the non-pulmonary heart disease group,the cor-relation analysis showed that the BNP levels were positively correlated with the MPV levels(r=0.357,P＜0.001),the BNP levels were negatively correlated with the PLT levels(r=-0.260,P=0.048),and the PLT levels were negatively correlated with the MPV levels(r=-0.340,P＜0.001).Conclusion BNP is of great significance in the diagnosis of pulmonary heart disease and the assessment of disease status.When combined with PLT and BNP,MPV can become an important clinical indicator for evaluating heart failure and suscepti-bility to thrombosis in patients with pulmonary heart disease.
万方数据
维普
