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肥胖者脑网络改变的研究进展

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肥胖所引发的神经毒性使得脑结构和脑网络发生改变,从而导致肥胖者的认知功能减退,进而阻碍身体机能的恢复,因此肥胖可能是一个关于身体和大脑的复合体疾病。相关研究发现,肥胖者脑网络的改变可能是导致肥胖伴认知障碍的主要原因。该文简要阐述了肥胖与脑网络改变的中介和调节因素,并探讨了肥胖者脑功能网络的异常机制,为筛查、预防、治疗和监测肥胖合并认知损害提供新策略。
Research progress on changes in brain networks in obese individuals
The neurotoxicity caused by obesity leads to changes in brain structure and network,resul-ting in cognitive decline in obese individuals and hindering the recovery of bodily functions.Therefore,obesity may be a complex disease related to the body and brain.Related studies have found that changes in the brain network of obese individuals may be the main cause of cognitive impairment associated with obesity.The arti-cle briefly elaborates on the mediating and regulatory factors between obesity and changes in brain networks,and explores the abnormal mechanisms of brain functional networks in obese individuals,providing new strat-egies for screening,preventing,treating,and monitoring obesity combined with cognitive impairment.

ObesityBrain networkNeuroimagingCognitive impairmentReview

罗伟强、罗光华、张洛恺

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南华大学附属第一医院放射影像中心,湖南衡阳 421001

肥胖 脑网络 神经影像学 认知损害 综述

湖南省研究生科研创新项目

CX20221011

2024

现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
年,卷(期):2024.40(8)
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