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头颈肿瘤放疗后咽鼓管功能障碍机制研究进展

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头颈部恶性肿瘤是常见的恶性肿瘤之一。头颈肿瘤放疗后分泌性中耳炎、粘连性中耳炎、中耳胆脂瘤、化脓性中耳炎、慢性乳突炎等中耳疾病发生率高,且治疗效果欠佳,严重影响患者生活质量。咽鼓管功能障碍是头颈恶性肿瘤放疗导致中耳疾病的核心因素,放疗导致咽鼓管功能障碍形成的机制较为复杂,该文从其形成机制方面进行了综述,旨在为临床治疗头颈肿瘤放疗后中耳疾病提供参考。
Research progress on the mechanism of eustachian tube dysfunction after radiotherapy for head and neck tumors
Head and neck malignant tumors are one of the common malignant tumors.T he incidence of middle ear diseases such as secretory otitis media,adhesive otitis media,middle ear cholesteatoma,purulent otitis media,and chronic mastoiditis is high after radiotherapy for head and neck tumors,and the treatment effect is poor,seriously affecting the quality of life of patients.Eustachian tube dysfunction is the core factor of middle ear disease caused by radiotherapy for head and neck malignant tumors.The mechanism of eustachian tube dysfunction caused by radiotherapy is relatively complex.The article reviews its formation mechanism,aiming to provide reference for clinical treatment of middle ear disease after radiotherapy for head and neck tumors.

Eustachian tube dysfunctionMiddle ear diseaseHead and neck tumorsRadiotherapy

邓锐、骆文龙、王朝永

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重庆医科大学,重庆 400016

咽鼓管功能障碍 中耳疾病 头颈肿瘤 放疗

重庆市科卫联合医学科研面上项目

2021MSXM279

2024

现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
年,卷(期):2024.40(8)
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