Comparison between imaging features and pathological basis of small cell lung cancer
Objective To investigate the typical CT imaging features of small cell lung cancer(SCLC)and the corresponding pathophysiological basis,in order to improve the understanding and diagnosis of SCLC.Methods The imaging data of 36 patients with SCLC confirmed by pathological examination admitted to the hospital from June 2016 to September 2023 were collected,and the CT plain scan,CT enhanced image signs and pathological basis were compared and analyzed.Results There were 28 males and eight females in the 36 patients.The median age was 62.05 years old.CT examination showed 31 cases of central SCLC(seven cases of left upper lobe,five cases of left lower lobe,five cases of left hilum,three cases of right upper lobe,four ca-ses of right lower lobe and seven cases of right hilum),including 20 cases of frozen mediastinum,12 cases of frozen hilum,nine cases of needle-like trachea,16 cases of vascular embedding sign,10 cases of clear pleural ef-fusion sign,22 cases of swamp-like enhancement,six cases of duck web sign,six cases of round and blunt edge of mass,and five cases of tiny sand-like calcification sign.There were five cases of peripheral SCLC(one case of right lower lung,one case of right upper lobe,one case of left lower lung and two cases of left upper lobe),in-cluding two cases of female pup large sign,three cases of worm sign,one case of subpleural hill sign and one case of peach tip sign at the edge of the mass.Secondary changes were pleural effusion in 15 cases,obstructive pneumonia in five cases,and obstructive atelectasis in two cases.Conclusion However,its pathological basis is related to the characteristics of SCLC cancer cells,such as large and deep staining of nucleus,less cytoplasm,dense cells,loose/chaotic tumor nests,less fiber components,short value-added time,rapid growth,weak con-tractility,strong invasiveness,soft lesions,and easy to be pushed and deformed.Although SCLC has various manifestations,there are some typical imaging signs,which have characteristic,but the diagnosis still needs to be combined with pathological examination.
Small cell lung cancerNeuroendocrine neoplasmsOat cellsTomography,X-Ray computerFrozen mediastinum
万方数据
维普
