Effect of TAO combined with rh-bFGF gel on symptom disappearance time and inflammatory factors in patients with deep second degree burn
Objective To investigate the efficacy of compound polymyxin B ointment(TAO)combined with recombinant bovine basic fibroblast growth factor(rh-bFGF)gel in the treatment of patients with deep second degree burns.Methods A total of 60 patients with deep Ⅱ degree burn admitted to our hospital from January to November 2022 were selected and divided into observation group and control group by random number table method,with 30 patients in each group.The control group was treated with TAO,and the obser-vation group was treated with rh-bFGF gel.The clinical efficacy,symptom disappearance time,wound healing time,dressing pain,inflammatory factors,incidence of complications,and quality of life were compared be-tween the two groups.Results The total effective rate of the observation group was significantly higher than that of the control group,the incidence of complications was significantly lower than that of the control group,the degree of pain was significantly lighter than that of the control group,the swelling disappearance time,ery-thema disappearance time,exudate disappearance time,blister disappearance time,pain disappearance time and wound healing time were significantly shorter than those of the control group,the differences were statistically significant(P＜0.05).There was no significant difference being found in the comparison of inflammatory fac-tors and quality of life between the two groups before treatment(P＞0.05).After treatment,the levels of pro-calcitonin and C-reactive protein in the observation group were significantly lower than those in the control group.The scores of basic living ability dimension,hand function dimension,emotional dimension,interperson-al relationship dimension,sexual life dimension,body heat dimension,heat sensitivity dimension,cooperation treatment dimension and work dimension in the simplified burn health scale were significantly higher than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion TAO com-bined with rh-bFGF gel is effective in the treatment of patients with deep Ⅱ degree burn.It can accelerate the disappearance of symptoms and wound healing,reduce the pain and inflammatory reaction of dressing change,reduce the incidence of complications and improve the quality of life of patients.
Deep Ⅱ degree burnCompound polymyxin B ointmentRecombinant bovine basic fi-broblast growth factor gelInflammatory factorQuality of life
万方数据
维普
