Research progress of short-chain fatty acids in pregnancy-related diseases
Pregnancy-related diseases refer to specific diseases during or related to pregnancy.Their complex pathogenesis and multiple etiologies may lead to various adverse consequences for pregnant women and newborns,and there is no effective treatment at present.As an important metabolite of intestinal microbi-ota,short-chain fatty acids(SCFAs)not only maintain the integrity of intestinal mucosal epithelium,but also play an important role in regulating glucose and lipid metabolism,immune inflammation and so on.In recent years,the mechanisms by which pregnancy-related diseases are associated with gut microbiota have been ex-tensively studied.Intestinal flora and metabolites can be used as new biomarkers to provide new ideas for diag-nosis and treatment of pregnancy-related diseases.This article reviewed the relationship and mechanism be-tween SCFAs and pregnancy-related diseases,so as to achieve the purpose of early diagnosis and intervention of adverse pregnancy outcomes and improve the prognosis of mothers and children.
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