Research progress of tertiary lymphoid tissues in chronic outcome of acute kidney injury
Acute kidney injury(AKI)is characterized by a rapid decline in glomerular filtration rate,which is an important risk factor for the occurrence and development of chronic kidney disease(CKD).A thorough understanding of this process is helpful to prevent AKI from progressing to CKD.Tertiary lymphoid tissues(TLTs)are formed by the aggregation of lymphocytes in non-lymphoid organs,which play a role in kidney diseases.This article reviewed the molecular mechanism of TLTs formation,the role of TLTs in the development of AKI to CKD,and the targeted therapeutic strategies.
国家科技期刊平台
NSTL
万方数据
