现代医药卫生2024,Vol.40Issue(11) :1879-1883.DOI:10.3969/j.issn.1009-5519.2024.11.016

临床药师对新生儿科美罗培南临床使用的干预研究

Intervention study of clinical pharmacists on clinical use of meropenem for injection in neonates

李云送 林万龙 黄志毅
现代医药卫生2024,Vol.40Issue(11) :1879-1883.DOI:10.3969/j.issn.1009-5519.2024.11.016

临床药师对新生儿科美罗培南临床使用的干预研究

Intervention study of clinical pharmacists on clinical use of meropenem for injection in neonates

李云送 1林万龙 1黄志毅1
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作者信息

  • 1. 厦门大学附属妇女儿童医院,福建 厦门 361003
  • 折叠

摘要

目的 通过某三甲妇儿专科医院临床药师对新生儿科使用美罗培南的干预分析,为新生儿科临床药师参与临床药学工作提供参考,促进临床规范使用美罗培南.方法 回顾性分析该院新生儿科临床药师未参与该科室临床查房前半年(2017年1-6月)所有使用美罗培南的病历123份(干预前组),参与该科室查房进行用药干预后(2020年1-6月)所有使用美罗培南病历70份(干预后组).研究比较新生儿科临床药师干预前后,美罗培南在适应证、用法用量及配伍、病原学及疗效评估、联合用药等方面的情况.结果 干预后组所有使用美罗培南的病历在适应证、用法用量、降阶梯时机,联合用药方面情况均较干预前组得到显著改善,差异均有统计学意义(P<0.05).结论 新生儿科临床药师深度参与临床工作进行用药干预,对碳青霉烯类抗菌药物的规范使用、持续改善起到较大推动作用.

Abstract

Objective To provide reference for clinical pharmacists in neonatology to participate in clini-cal pharmacy and to promote the standardized clinical use of Meropenem through the analysis of the interven-tion of clinical pharmacists on the use of Meropenem in neonatology in a tertiary care women's and children's specialty hospital.Methods Retrospective analysis of 123 medical records of all Meropenem use in the neona-tology department of the hospital in the six months(January-June 2017)before the clinical pharmacist did not participate in the clinical checkup of the department(pre-intervention group),and 70 medical records of all Meropenem use after the participation(January-June 2020)in the checkup of the department for medication in-tervention(post-intervention group).The study compared Meropenem before and after the clinical pharmacist intervention in the neonatal unit in terms of indications,dosage and dosing,pathogenetic and efficacy assess-ment,and co-administration of Meropenem.Results After the intervention,all the medical records of Mero-penem in the post-intervention group were significantly improved in terms of indications,dosage,timing of step-downs,and combinations compared with those of the pre-intervention group,and the differences were sta-tistically significant(P<O.05).Conclusion The deep involvement of clinical pharmacists in the neonatal de-partment in clinical work for medication intervention plays a greater role in promoting the standardized use and continuous improvement of carbapenem antimicrobials.

关键词

美罗培南/新生儿科/临床药师/用药干预

Key words

Meropenem/Neonatal Pediatrics/Clinical pharmacist/Medication intervention

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出版年

2024
现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
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