Intervention study of clinical pharmacists on clinical use of meropenem for injection in neonates
Objective To provide reference for clinical pharmacists in neonatology to participate in clini-cal pharmacy and to promote the standardized clinical use of Meropenem through the analysis of the interven-tion of clinical pharmacists on the use of Meropenem in neonatology in a tertiary care women's and children's specialty hospital.Methods Retrospective analysis of 123 medical records of all Meropenem use in the neona-tology department of the hospital in the six months(January-June 2017)before the clinical pharmacist did not participate in the clinical checkup of the department(pre-intervention group),and 70 medical records of all Meropenem use after the participation(January-June 2020)in the checkup of the department for medication in-tervention(post-intervention group).The study compared Meropenem before and after the clinical pharmacist intervention in the neonatal unit in terms of indications,dosage and dosing,pathogenetic and efficacy assess-ment,and co-administration of Meropenem.Results After the intervention,all the medical records of Mero-penem in the post-intervention group were significantly improved in terms of indications,dosage,timing of step-downs,and combinations compared with those of the pre-intervention group,and the differences were sta-tistically significant(P<O.05).Conclusion The deep involvement of clinical pharmacists in the neonatal de-partment in clinical work for medication intervention plays a greater role in promoting the standardized use and continuous improvement of carbapenem antimicrobials.