Research progress on the damage of carbon nanotubes to vascular endothelial cells
Carbon nanotubes as novel nanomaterials,which are widely used in biomedical field.Through the respiratory tract,digestive tract,and circulation,carbon nanotubes can come into contact with vascular en-dothelial cells and damage the endothelial cells.In this paper,the factors effecting the damage of carbon nano-tubes to endothelial cells was reviewed,and the effects of carbon nanotubes on endothelial cell inflammation,monocyte adhesion,lipid accumulation,endothelial permeability,angiogenesis,and pro-coagulant ability were reviewed.Meanwhile,this paper reviewed that carbon nanotubes promote the formation of atherosclerotic plaques and the impairment of blood-brain barrier function by damaging endothelial cells in animal experi-ments,so as to provide a reference for decision-making on the application of carbon nanotubes in biomedical field.
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