Carbon nanotubes as novel nanomaterials,which are widely used in biomedical field.Through the respiratory tract,digestive tract,and circulation,carbon nanotubes can come into contact with vascular en-dothelial cells and damage the endothelial cells.In this paper,the factors effecting the damage of carbon nano-tubes to endothelial cells was reviewed,and the effects of carbon nanotubes on endothelial cell inflammation,monocyte adhesion,lipid accumulation,endothelial permeability,angiogenesis,and pro-coagulant ability were reviewed.Meanwhile,this paper reviewed that carbon nanotubes promote the formation of atherosclerotic plaques and the impairment of blood-brain barrier function by damaging endothelial cells in animal experi-ments,so as to provide a reference for decision-making on the application of carbon nanotubes in biomedical field.
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