Intervention effect of cluster nursing in patients with diarrhea caused by oral pyrrotinib tablets
Objective To explore the intervention effect of cluster nursing in patients with diarrhea caused by oral pyrrotinib tablets.Methods A total of 100 patients with advanced breast cancer admitted to the hospital from March 2022 to February 2023 were selected and divided into the control group and the obser-vation group according to random number table,with 50 patients in each group.Both groups were treated with pyrrotinib.The control group performed routine nursing care,and the observation group performed cluster nursing care.The grade of diarrhea degree,the improvement of diarrhea symptoms,medication compliance and the occurrence of adverse reactions were compared between the two groups.Both groups maintained continu-ous care for one week.Results The grade of diarrhea in the observation group was better than that of the con-trol group,and the difference was statistically significant(Z=-2.377,P=0.017).The number of diarrhea in the observation group was(4.01±0.98),which was less than that in the control group(6.69±1.20),and the diarrhea recovery time was(3.06±0.22)d,which was shorter than that in the control group(5.12±0.33)d,the differences were statistically significant(t=12.232,P＜0.001;t=36.727,P＜0.001).The medication compliance[96.00％(48/50)]in the observation group was higher than that in the control group[84.00％(42/50)],the incidence of adverse reactions in the observation group[6.00％(3/50)]was lower than that in the control group[22.00％(11/50)],and the differences were statistically significant(X2=4.000,P=0.046;X2=5.316,P=0.021).Conclusion Cluster nursing intervention measures have good application effects in patients with oral pyrrolitinib tablets,which is conducive to improving their medication compliance,reducing the sever-ity of diarrhea,which is beneficial for patient prognosis.
Breast cancerPyrrolitinibCluster nursingDiarrheaValiditySecurity
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