SARC-CalF量表对亚洲老年人群肌肉减少症诊断价值的 meta 分析
Diagnostic value of SARC-CalF scale for sarcopenia in Asian elderly population:A meta-analysis
邓雅 1周星辰 1黄龄漪 1郭声敏2
作者信息
- 1. 西南医科大学护理学院,四川 泸州 646000
- 2. 西南医科大学附属医院护理部,四川 泸州 646000
- 折叠
摘要
目的 系统评价SARC-CalF量表筛检亚洲老年人群肌肉减少症风险的效果.方法 检索PubMed、Web of Science、Embase、Cochrane Library、CIN AHL、中国知网、中国生物医学文献数据库、维普、万方中使用SARC-CalF量表筛查亚洲老年人群肌肉减少症的诊断/筛检试验研究,检索时间为建库至2023年4月.采用诊断准确性研究质量评价工具(QUADAS-2)对纳入文献进行质量评价,资料分析采用STATA15.1.结果 共纳入12篇文献,筛查老年人肌肉减少症5 406例,meta分析结果显示,SARC-CalF量表筛查老年人群肌肉减少症的合并敏感度为0.63[95％可信区间(95％CI)0.54～0.71],合并特异度为0.82(95％CI 0.74～0.88),阳性似然比为3.40(95％CI 2.50～4.80),阴性似然比为0.45(95％CI 0.37～0.56),诊断比值比为8(95％CI 5～12),拟合受试者操作特征曲线下面积(AUC)为0.78(95％CI 0.74～0.81).结论 SARC-CalF量表对亚洲老年人群肌肉减少症筛查具有一定准确性,且不同研究人群、地区的诊断价值存在差异,但具体情况仍需联用其他筛查工具以提高敏感度,避免漏诊.
Abstract
Objective To systematically evaluate the effect of SARC-CalF scale on screening the risk of sarcopenia in Asian elderly population.Methods The PubMed,Web of Science,Embase,Cochrane Library,CINAHL,CNKI,CBM,VIP and Wanfang for diagnostic/screening trials of SARC-CalF for sarcopenia in Asi-an elderly population were searched from inception to April 2023.The diagnostic accuracy research quality e-valuation tool(QUADAS-2)was used to evaluate the quality of the included literature,and STATA15.1 was used for data analysis.Results A total of 12 literatures were included,and 5 406 cases of sarcopenia in the eld-erly were screened.The results of meta-analysis showed that the combined sensitivity of SARC-CalF scale for screening sarcopenia in the elderly was 0.63[95％confidence interval(95％CI)0.54-0.71],the combined specificity was 0.82(95％CI 0.74-0.88),the positive likelihood ratio was 3.40(95％CI 2.50-4.80),the negative likelihood ratio was 0.45(95％CI 0.37-0.56),and the diagnostic odds ratio was 8(95％CI 5-12).The area under the receiver operating characteristic curve(AUC)was 0.78(95％CI 0.74-0.81).Conclusion SARC-CalF scale has certain accuracy in screening sarcopenia in Asian elderly population,and the diagnostic value of different research populations and regions is different.However,other screening tools are still needed to im-prove the sensitivity and avoid missed diagnosis.
关键词
SARC-CalF量表/老年人/肌肉减少症/诊断/Meta分析Key words
SARC-CalF scale/Elderly/Muscle reduction/Diagnosis/Meta-analysis引用本文复制引用
基金项目
国家卫生健康委医院管理研究所重点项目(YLZLXZ22K011)
出版年
2024
国家科技期刊平台
NSTL
万方数据