Research progress on the neuroprotective mechanism of exercise therapy on cerebral hemorrhage
Intracerebral hemorrhage(ICH)is a serious disease that endangers human health.Dysfunc-tion after ICH brings a high disability rate and has become a serious public health problem.Therefore,it is very important to explore effective rehabilitation methods for the prevention and treatment of ICH.The effec-tiveness of exercise therapy in improving dysfunction after ICH is obvious.It can promote angiogenesis,nerve regeneration and synaptic plasticity,and reduce inflammatory response,oxidative stress and apoptosis after ICH to play a neuroprotective role.However,the molecular mechanism by which exercise therapy plays a neu-roprotective role in ICH remains unknown.Therefore,this article reviewed the clinical and animal experimen-tal evidence of exercise therapy in the prevention and treatment of ICH,in order to reveal the potential neuro-protective mechanism of exercise therapy,and provide a theoretical basis for exercise therapy in the field of ICH functional rehabilitation.