心力衰竭与钙循环蛋白关系的研究进展
Research progress of relationship between heart failure and calcium circulating protein
刘兰 1邹操2
作者信息
- 1. 苏州大学附属第一医院心内科,江苏苏州 215006;湖北科技学院附属浠水医院心内科,湖北黄冈 438200
- 2. 苏州大学附属第一医院心内科,江苏苏州 215006
- 折叠
摘要
心力衰竭是各种疾病的终末期,是全世界发病率和死亡率的主要原因,被称为心血管领域的最后"战场".心力衰竭的发病机制多样复杂,异常的心肌细胞钙循环是心力衰竭发生的主要病理生理变化之一.钙循环的改变是衰竭心肌收缩功能障碍和心律失常发生的主要原因.心功能障碍与钙循环蛋白、钙通道和钙泵的变化密切相关.因此,深入了解钙循环蛋白和心力衰竭的关系对于心力衰竭治疗和预后的研究有重要意义.
Abstract
Heart failure is the end-stage of various diseases and the leading cause of morbidity and mor-tality worldwide.It is known as the final"battlefield"in the cardiovascular field.The pathogenesis of heart failure is diverse and complex.Abnormal myocardial cell calcium circulation is one of the main pathophysio-logical changes in heart failure.The change of calcium cycle is the main cause of myocardial systolic dysfunc-tion and arrhythmia.Cardiac dysfunction is closely related to the changes of calcium circulating protein,calci-um channel and calcium pump.Therefore,an in-depth understanding of the relationship between calcium cir-culating protein and heart failure is of great significance for the study of the treatment and prognosis of heart failure.
关键词
钙循环蛋白/心力衰竭/综述Key words
Calcium circulating protein/Heart failure/Review引用本文复制引用
基金项目
苏州市卫生青年骨干全国导师制培训项目(H190426)
湖北科技学院医学部教研项目(2023YJDJY010)
出版年
2024
国家科技期刊平台
NSTL
万方数据