Research progress of relationship between heart failure and calcium circulating protein
Heart failure is the end-stage of various diseases and the leading cause of morbidity and mor-tality worldwide.It is known as the final"battlefield"in the cardiovascular field.The pathogenesis of heart failure is diverse and complex.Abnormal myocardial cell calcium circulation is one of the main pathophysio-logical changes in heart failure.The change of calcium cycle is the main cause of myocardial systolic dysfunc-tion and arrhythmia.Cardiac dysfunction is closely related to the changes of calcium circulating protein,calci-um channel and calcium pump.Therefore,an in-depth understanding of the relationship between calcium cir-culating protein and heart failure is of great significance for the study of the treatment and prognosis of heart failure.