Observation on the therapeutic effect of laxative paste combined with'Si'formula on opioid-related constipation in patients with cancer pain
Objective To explore the clinical effect of laxative paste combined with'Si'formula in the treatment of opioid-related constipation.Methods From April to December 2022,a total of 70 patients with tumor who received oral administration of oscondin or mifekon for analgesia were selected and randomly divid-ed into control group and experimental group,with 35 cases in each group.The control group was given rou-tine nursing,and the experimental group was given laxative paste combined with'Si Zi Jue'tona method.Af-ter 14 days of intervention,the incidence of constipation,fecal character score,other constipation symptom score,TCM syndrome score and quality of life score(PAC-QOL)were compared between the two groups.Re-sults Constipation occurred in 11 patients in the experimental group,which was lower than that in the control group(21 cases).The scores of fecal traits,other constipation symptoms,total scores of TCM syndromes and PAC-QOL scores in the experimental group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Bowel patch combined with'Si'formula can reduce the incidence of opioid-related constipation in cancer patients,relieve constipation symptoms and improve the qual-ity of life of patients.
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