急性淋巴细胞白血病患儿医院感染防控对策研究
Research on prevention and control of nosocomial infection in children with acute lymphoblastic leukemia
王勤 1毛彦娜 2王俊 1刘慧萍 1林佳2
作者信息
- 1. 郑州大学附属儿童医院/河南省儿童医院/郑州儿童医院 感染防控科,河南 郑州 450018
- 2. 郑州大学附属儿童医院/河南省儿童医院/郑州儿童医院 血液肿瘤科,河南 郑州 450018
- 折叠
摘要
目的 探讨急性淋巴细胞白血病患儿医院感染的防控对策.方法 选取2019年1月至2022年6月该院血液肿瘤科收治的282例急性淋巴细胞白血病住院患儿,将其随机分为对照组(n=138)、观察组(n=144),2组均实施常规治疗及护理措施,观察组增加预防医院感染防控对策,对比2组患儿医院感染率、感染部位及总体健康水平.结果 对照组患儿共发生医院感染22例25例次,观察组共发生医院感染10例12例次,对照组、观察组患儿医院感染发生率分别为15.94%、6.94%,对照组、观察组患儿医院感染例次发生率分别为18.12%、8.33%,观察组患儿医院感染发生率、医院感染例次发生率均低于对照组,差异均有统计学意义(P<0.05);感染主要部位为上呼吸道,革兰阴性菌为主要感染病原菌;观察组生活质量(QOL)评分[(69.87±3.41)分]高于对照组[(63.88±3.09)分],差异有统计学意义(P<0.05).结论 对急性淋巴细胞白血病采取感染防控对策可有效降低患儿医院感染发生率,提高其总体健康水平,有效缓解负性情绪.
Abstract
Objective To investigate strategies for preventing and controlling hospital acquired infec-tions in children with acute lymphoblastic leukemia(ALL).Methods From January 2019 to June 2022,a total of 282 hospitalized children with acute lymphoblastic leukemia were enrolled from the Department of Hema-tology and Oncology of our hospital.They were randomly divided into the control group(n=138)and the ob-servation group(n=144).Both groups received standard treatment and nursing care,while the observation group additionally implemented measures for preventing hospital acquired infections.The study compared the incidence of hospital acquired infections,infection sites,and overall health status between the two groups.Re-sults In the control group,there were 22 cases and 25 episodes of hospital acquired infections,while in the ob-servation group,there were 10 cases and 12 episodes.The incidence rates of hospital acquired infections were 15.94%and 6.94%in the control and observation group,respectively,with corresponding episode rates of 18.12%and 8.33%.Both infection rates and episode rates were significantly lower in the observation group compared to the control group(P<0.05).Upper respiratory tract was the predominant site of infection,with Gram-negative bacteria being the main pathogens identified.The Quality of Life(QOL)score in the observa-tion group(69.87±3.41)was significantly higher than that in the control group(63.88±3.09)(P<0.05).Conclusion Implementing infection prevention and control strategies effectively reduces the incidence of hos-pital acquired infections in children with acute lymphoblastic leukemia,improves their overall health status,and mitigates negative emotional impacts.
关键词
急性淋巴细胞白血病/恶性肿瘤/医院感染/防控对策Key words
Acute lymphoblastic leukemia/Malignancy/Hospital acquired infection/Infection control strategies引用本文复制引用
基金项目
河南省医学科技攻关计划联合共建项目(LHGJ20230592)
出版年
2024
国家科技期刊平台
NSTL
万方数据