Research on prevention and control of nosocomial infection in children with acute lymphoblastic leukemia
Objective To investigate strategies for preventing and controlling hospital acquired infec-tions in children with acute lymphoblastic leukemia(ALL).Methods From January 2019 to June 2022,a total of 282 hospitalized children with acute lymphoblastic leukemia were enrolled from the Department of Hema-tology and Oncology of our hospital.They were randomly divided into the control group(n=138)and the ob-servation group(n=144).Both groups received standard treatment and nursing care,while the observation group additionally implemented measures for preventing hospital acquired infections.The study compared the incidence of hospital acquired infections,infection sites,and overall health status between the two groups.Re-sults In the control group,there were 22 cases and 25 episodes of hospital acquired infections,while in the ob-servation group,there were 10 cases and 12 episodes.The incidence rates of hospital acquired infections were 15.94%and 6.94%in the control and observation group,respectively,with corresponding episode rates of 18.12%and 8.33%.Both infection rates and episode rates were significantly lower in the observation group compared to the control group(P<0.05).Upper respiratory tract was the predominant site of infection,with Gram-negative bacteria being the main pathogens identified.The Quality of Life(QOL)score in the observa-tion group(69.87±3.41)was significantly higher than that in the control group(63.88±3.09)(P<0.05).Conclusion Implementing infection prevention and control strategies effectively reduces the incidence of hos-pital acquired infections in children with acute lymphoblastic leukemia,improves their overall health status,and mitigates negative emotional impacts.
Acute lymphoblastic leukemiaMalignancyHospital acquired infectionInfection control strategies
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