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缺血性脑卒中脑水肿研究进展

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缺血性脑卒中脑水肿是缺血性脑卒中后脑损伤的重要因素。目前,对缺血性脑卒中脑水肿的深层次机制了解还不够充分,已有的机制复杂且处于动态变化中,临床上尚缺乏普遍有效的预防和治疗手段。该文综述了缺血性脑卒中脑水肿病理变化及检测、治疗相关的研究进展,以期为缺血性脑卒中脑水肿的进一步研究及临床上有效预防、检测、治疗手段的开发提供思路。
Research progress on cerebral edema in ischemic stroke
Cerebral edema is an important factor in brain damage after ischemic stroke.At present,the deep-level mechanism of cerebral edema in ischemic stroke is not fully understood.The existing mechanisms are complex and dynamically changing,and there is still a lack of universally effective prevention and treat-ment methods in clinical practice.This article reviewed the research progress related to the pathological chan-ges,detection,and treatment of ischemic stroke cerebral edema,with a view to providing ideas for further re-search on ischemic stroke cerebral edema and the development of clinically effective prevention,detection,and treatment methods.

Ischemic strokeCerebral edemaCytotoxic cerebral edemaVasogenic cerebral ede-ma

陈红、郑小红、苏湲淇、徐晓玉、薛强

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陆军军医大学第一附属医院药剂科,重庆 400037

重庆医药高等专科学校,重庆 401331

西南大学药学院,重庆 400030

缺血性脑卒中 脑水肿 细胞毒性脑水肿 血管源性脑水肿

国家自然科学基金面上项目国家科技重大新药创制专项项目重庆市基础研究与前沿探索项目重庆市教委科学技术研究计划青年项目

814735492014ZX09304-306-04cstc2018jcyjA0749KJQN202202815

2024

现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
年,卷(期):2024.40(14)