Research progress on the relationship between mechanosensitive ion channel protein Piezo1 and clinical diseases
Piezo1 protein,as a novel mechanosensitive ion channel closely related to mechanical stress stimulation signals,plays a significant role in responding to mechanical stimulation and motion effects.This protein is widely distributed in the organs and tissues of the body,and has been widely concerned by the aca-demic community since its discovery.A number of highly successful scientific studies have shown that Piezo1 has important implications for the treatment of vascular,neurological,skeletal,immune,tumor and other dis-eases.Therefore,this paper reviewed the biological characteristics of Piezo1 and its correlation with clinical diseases,which provides new ideas and prospects for the study of the pathogenesis,diagnosis,treatment and prognosis monitoring of clinically related diseases.