Research progress of the association between subclinical cardiovascular disease and polycystic ovary syndrome
Polycystic ovary syndrome(PCOS)affects about 6%-10%of women all over the world and is characterized by hyperandrogenism,menstrual irregularities,infertility,and ultrasonographic polycystic ova-ries.In addition,PCOS is related to most of endocrine and metabolic disorders,including insulin resistance,o-besity and diabetes,hypertension,dyslipidemia,and metabolic syndrome,all of which increase the risk of sub-clinical cardiovascular disease(CVD),but only with changes in vascular endothelial function without signifi-cant CVD symptoms.By searching the latest literature,this paper summarized the relevant evidence of the re-lationship between PCOS patients and subclinical CVD,including flow-mediated dilation(FMD),arterial stiff-ness,coronary artery calcium(CAC)score,visceral and epicardial fat and carotid intima-media thickness(CI-MT)and so on,to better illustrate the relationship and the latest research progress between the PCOS pa-tients with subclinical CVD.
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