Role of sphingolipids and their metabolites in tumorigenesis and progression
Sphingolipids are widely present in cell membranes and participate in biological processes such as cell signaling,cell proliferation,migration,invasion and apoptosis.Sphingolipids and their metabolites play important roles in the occurrence and development of tumors,including promoting tumor cell prolifera-tion,migration and invasion,inhibiting tumor cell apoptosis and promoting immune escape.In recent years,the role of sphingolipids in a variety of tumors has been found.At present,sphingolipids and their metabolites have become a research hotspot in tumor treatment.This article mainly described the role and application prospect of sphingolipids and their metabolites in the occurrence and development of breast cancer,ovarian cancer,pancreatic cancer,colorectal cancer and other tumors.
国家科技期刊平台
NSTL
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