Study on laser surgery assisted with Leizumab for type Ⅱ diabetes retinopathy
Objective To investigate the effect of laser surgery assisted with Leizumab on retinal thick-ness and visual acuity recovery in patients with type Ⅱ diabetes retinopathy(DR).Methods A total of 140 type Ⅱ DR patients in Hopeshine-Minsheng Hospital of Xinzheng from February 2021 to February 2023 were selected retrospectively,and divided into the control group(70 cases)and the observation group(70 cases)ac-cording to different surgical methods.The control group received laser treatment,while the observation group received laser surgery assisted by Leizumab.The visual acuity levels,time to clinical symptom improvement,hemodynamic levels[end diastolic blood flow velocity(EDV),peak blood flow velocity(PSV),blood flow re-sistance index(RI)],low-vision quality of life(CLVQOL)scores,and incidence of complications between two groups were compared.Results The observation group had shorter absorption times for exudate,fundus hem-orrhage,and retinal edema compared to the control group,with statistical significance(P＜0.05).The obser-vation group had higher visual acuity and the best corrected visual acuity at one month after surgery,and the grayscale value and retinal thickness of the field of view were smaller than those of the control group,with statistical significance(P＜0.05).The EDV and PSV levels in the observation group were higher than those in the control group one month after surgery,while the RI levels were lower than those in the control group,with statistical significance(P＜0.05).The CLVQOL score of the observation group was higher than that of the control group one month after surgery,and the difference was statistically significant(P＜0.05).The inci-dence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion Laser surgery assisted with Leizumab can promote blood circulation in the eyes of type Ⅱ DR patients,reduce retinal thickness,improve vision,reduce the incidence of postoperative complications,and improve postoperative quality of life.
万方数据
维普
