Research progress of placental growth factor in predicting preeclampsia
Pre-eclampsia,which mostly occurs often after 20 weeks of gestation,severely affects mater-nal and fetal health and is a major cause of increased maternal and perinatal mortality worldwide.Therefore,it is important to explore biomarkers that can expedite the diagnosis of preeclampsia.Establishing a diagnostic model for preeclampsia in early and mid-pregnancy is a top priority for reducing maternal and infant mortali-ty.In this article,we review the pathogenesis of pre-eclampsia and the clinical application of angiogenic mark-ers such as placental growth factor,with the aim of improving the early diagnosis of pre-eclampsia and reduc-ing the risk of maternal complications and perinatal morbidity and mortality.
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