Research progress on the pathogenesis of geriatric frailty
Geriatric frailty is a complex syndrome faced by the elderly,which is characterized by the de-crease of physiological reserve and imbalance of multiple organ systems,which leads to the decrease of self-stability ability,the weakening of daily activity ability and the decline of quality of life.With the aging of the population,frailty is gradually becoming a public health problem that threatens the health of the elderly,seri-ously affecting the quality of life and clinical outcomes of the elderly.The pathogenesis of geriatric frailty is a complex process,including inflammatory response,cell senescence,intestinal flora disorder,insulin resistance,neuroendocrine disorders and other effects.This article reviews the pathogenesis of frailty in the elderly,and provides clues and basis for identifying risk factors for frailty,formulating corresponding prevention and inter-vention strategies,delaying frailty in the elderly,and improving the quality of life of the elderly.
国家科技期刊平台
NSTL
万方数据
