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妊娠合并噬血细胞综合征1例

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该院收治1例以发热合并贫血为首发症状的妊娠合并噬血细胞综合征(HPS)患者,26岁,孕周31+5 周,孕3产2。患者发生原因不明的发热、贫血和血小板减少,入院后积极进行相关检查,确诊为继发性HPS,予以地塞米松和免疫球蛋白治疗。经血液科、产科及新生儿科会诊后确定胎儿促肺成熟已完成,对患者实施子宫下段剖宫产术,术后患者及新生儿一般状况良好。患者转至血液科进行HPS的治疗,使用地塞米松加依托泊苷治疗1个疗程后,复查患者骨髓、凝血、血常规恢复良好,准予出院,出院后2周门诊复查患者恢复良好。
A case of pregnancy complicated with hemophagocytic syndrome
A case of pregnancy complicated with hemophagocytic syndrome(HPS)with fever com-bined with anemia as the first symptom was admitted to our hospital.The patient was 26 years old,31+5 weeks pregnant,3 pregnancies and 2 births.The patient experienced unexplained fever,anemia,and thrombo-cytopenia.After admission,extensive tests confirmed a diagnosis of secondary HPS,and she was treated with dexamethasone and intravenous immunoglobulin.Following consultations with the departments of hematolo-gy,obstetrics,and neonatology,it was determined that fetal lung maturation was complete.The patient under-went a lower segment cesarean section.Both the patient and the newborn were in good general condition post-operatively.The patient was then transferred to the hematology department for further treatment of HPS and underwent one course of treatment with dexamethasone and etoposide.A follow-up examination of her bone marrow,coagulation profile,and complete blood count showed good recovery,and she was discharged.The pa-tient remained well at a two-week post-discharge outpatient follow-up.

Hemophagocytic syndromePregnancyCase reports

蒙洁、黄继山、成星、张翀、米乐园

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甘肃省妇幼保健院/甘肃省中心医院:检验科,甘肃 兰州 730000

甘肃省妇幼保健院/甘肃省中心医院:妇产重症医学科,甘肃 兰州 730000

噬血细胞综合征 妊娠 病例报告

2024

现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
年,卷(期):2024.40(17)