Research progress on the relationship between Angiotensin Ⅱ and its receptor and circulatory diseases
Angiotensin Ⅱ(Ang Ⅱ)is the main active peptide in renin angiotensin system(RAS),which is closely related to the occurrence and development of circulatory diseases such as heart disease,hyper-tension,hyperlipidemia and stroke.Ang Ⅱ not only participates in the beneficial effects of regulating blood pressure stability and maintaining water and salt balance,but also promotes vascular inflammatory response,causes oxidative stress injury,vascular endothelial dysfunction and circulatory system diseases.The role of Ang Ⅱ in the occurrence and development of circulatory system diseases has always been the focus of academ-ic research.Therefore,clarifying the relationship between Ang Ⅱ and circulatory system diseases can provide new ideas for clinical treatment of circulatory system diseases.
Angiotensin ⅡAngiotensin Ⅱ receptorDisease of the circulatory systemReview