Effect of breathing exercises on prognosis in patients with chronic heart failure:A meta-analysis
Objective To systematically evaluate the effects of breathing exercises on cardiopulmonary function,exercise endurance and quality of life in patients with chronic heart failure(CHF).Methods Com-puterized searches of CNK1,Wanfang,VIP,PubMed,EBSCO,Embase,Web of Science,The Cochrane Library,SinoMed,and other databases were conducted to retrieve information on the effects of cardiopulmonary func-tion,exercise tolerance,and quality of life in patients with CHF from inception to December 2023 in a series of randomized controlled trials(RCT).Two researchers independently performed literature screening,data ex-traction and quality evaluation.Finally,meta-analysis was performed using RevMan 5.4 software.Pulmonary function indexes included peak oxygen uptake(PeakVO2)and carbon dioxide ventilation equivalent slope(VE/VCO2 slope).Cardiac function indexes included left ventricular ejection fraction(LVEF)and brain natri-uretic peptide precursor(NT-proBNP).PeakVO2 and six min walking test(6MWT)were used to evaluate ex-ercise tolerance.Minnesota heart failure quality of life scale(MLHFQ)was used to evaluate quality of life.Re-sults A total of 13 RCTs literature involving 900 patients were included.Compaired with control group,the descriptive results showed that breathing exercises of obviouse group significantly enhanced PeakVO2[stan-dardizd mean deviation(SMD)=0.47,95％confidence interal(95％CI)0.03-0.91,P=0.04],VE/VCO2[mean difference(MD)=-3.20,95％CI-4.49--1.19,P＜0.001],improved NT-proBNP(MD=-134.25,95％CI-141.95--126.56,P＜0.001),LVEF(SMD=0.53,95％CI 0.16-0.90,P=0.005),6MWT(MD=77.71,95％CI 69.50-85.92,P＜0.001),MLHFQ(MD=-7.68,95％CI-8.99--6.37,P＜0.001).Conclusion Breathing exercises can significantly increase lung function and exercise tolerance in patients with CHF,and improve cardiac function and quality of life of them to a certain extent.
Breathing exercisesChronic heart failureCardiopulmonary functionExercise toler-anceQuality of life
万方数据
维普
