Research progress on the mechanism of mass effect in neural injury after intracerebral hemorrhage
Intracerebral hemorrhage(ICH)is a critical neurological disease caused by the rupture of blood vessels within the brain parenchyma,with high mortality and morbidity rates.Currently,much research has focused on the injury mechanisms and intervention strategies following ICH,yet clinically effective treat-ments that significantly improve patient outcomes remain scarce.The mass effect refers to the mechanical compression of brain tissue by the hematoma during ICH,and its crucial role in neural function damage has been widely recognized in clinical practice.Therefore,exploring the mechanisms and pathways of the mass effect mediating primary and secondary injuries after ICH holds significant practical importance for the devel-opment of clinical intervention strategies.This article reviews the injury mechanisms and pathways of the mass effect during the onset and progression of ICH,aiming to provide references and theoretical bases for in-tervention research following ICH.