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不同运动强度对老年ST段抬高型心肌梗死患者长期衰弱发生的影响

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目的 明确不同运动强度对老年ST段抬高型心肌梗死(STEMI)患者长期衰弱发生的影响。方法 连续纳入2019年1月至2022年12月于该院住院的年龄大于或等于60岁的STEMI患者688例,根据患者不同的运动强度,将其分为标准强度运动组和低强度运动组,每组344例。使用FRAIL衰弱评估量表评估患者长期衰弱情况和心血管预后。结果 平均随访时间(2。63±0。41)年,衰弱发病率为27。9%。标准强度运动组年龄和糖化血红蛋白水平更低,男性比例更高、每周运动时间和每日运动时间更久,差异均有统计学意义(P<0。05)。随访时标准强度运动组发生心绞痛和衰弱的比例更低,NYHA心功能分级更优,FRAIL衰弱评分的水平更低,差异均有统计学意义(P<0。001)。多因素logistic回归分析显示,年龄、糖尿病史、每周运动时间和每日运动时间可能对STEMI患者长期衰弱的发生产生独立影响(P<0。05),基于此构建STEMI患者发生长期衰弱的预测模型,该模型预测衰弱发生的效能较好[曲线下面积(AUC)=0。697,95%可信区间(95%CI)0。618~0。775,P<0。001]。结论 STEMI患者院外进行标准强度的运动可以减少长期衰弱的发生。医务人员应进一步加强对STEMI患者运动康复的宣传和指导。
The effect of different exercise intensities on long-term frailty in STEMI patients
Objective To clarify the effect of different exercise intensities on long-term frailty in ST el-evation myocardial infarction(STEMI)patients.Methods A tatal of 688 STEMI patients admitted to our hospital between January 2019 and December 2022 were continuously included.Based on their weekly exercise intensity,the patients were divided into the standard-intensity group and the low-intensity group,344 cases in each group.Collected basic information during hospitalization and conducted long-term follow-up.Used the FRAIL frailty assessment scale to evaluate long-term frailty and cardiovascular outcomes.Results The aver-age follow-up time was(2.63±0.41)years,and the incidence rate of frailty was 27.9%.The proportion of men,the level of weekly exercise days and daily exercise time was higher(P<0.05)in the standard-intensity group.During follow-up,the standard-intensity group had a lower incidence of angina and frailty,a higher pro-portion of grade in NYHA heart function classification,and a lower level of FRAIL frailty score(P<0.001).Multivariate logistic regression analysis showed that age,diabetes history,weekly exercise days and daily exer-cise time may have an independent impact on the occurrence of long-term frailty in STEMI patients(P<0.05).Based on this,a prediction model of long-term frailty in STEMI patients was constructed,and the model was effective in predicting the occurrence of frailty(AUC=0.697,95%CI 0.618-0.775,P<0.001).Conclusion Standard intensity exercise outside the hospital for STEMI patients can reduce the occurrence of long-term frailty and improve patient prognosis.Medical staff should further strengthen the promotion and guidance of exercise rehabilitation for STEMI patients.

ST elevation myocardial infarctionExercise trainingFrailtyPrognosisAged

尹晓凤、刘刚、罗素新、沈健

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重庆医科大学附属第一医院心血管内科,重庆 400016

ST段抬高型心肌梗死 运动训练 衰弱 预后 老年人

2024

现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
年,卷(期):2024.40(19)