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血液透析患者跌倒风险预测模型的构建与效能分析

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目的 研究血液透析患者跌倒发生的风险因素,构建预测模型,并进行内部及外部验证。方法 选择2022年1月至2023年1月在该院肾内科接受门诊血液透析治疗的200例患者作为研究对象,此部分患者作为训练集。另选择2023年2月至2024年2月在同一所医院接受血液透析的50例患者作为研究的验证集。收集患者一般资料、临床资料,并对其进行为期1年的随访。分析血液透析患者跌倒的风险因素,构建列线图预测模型,并用受试者工作特征(ROC)曲线、Hosmer-Lemeshow检验验证模型的区分度和拟合优度。结果 根据研究对象是否跌倒分为跌倒组(n=79)和对照组(n=121),该院血液净化中心的患者跌倒发生率为39。5%。单因素Logistic回归分析显示,年龄、视力受损、使用助行工具、透析前舒张压、血钾、自理能力评分、糖尿病、脑卒中、使用降糖药、使用安眠药均是血液透析患者跌倒的风险因素(P<0。05)。多因素Logistic回归分析显示,使用助行工具、血钾(≥4。65 mmol/L)、自理能力评分(≤83分)、患有脑卒中、使用安眠药均是造成血液透析患者跌倒发生的独立危险因素(P<0。05)。ROC曲线下面积为0。796,其灵敏度和特异度分别为64。8%和89。9%;Hosmer-Lemeshow检验,x2=5。041,P=0。283。结论 该研究构建的风险预测模型能较好地预测血液透析患者的跌倒风险,为临床制定预防跌倒方案提供证据。
Construction and efficacy of fall risk prediction model for hemodialysis patients
Objective To explore the risk factors for falls in hemodialysis patients,construct a predic-tive model,and conduct internal and external validation.Methods A total of 200 patients who received outpa-tient hemodialysis treatment in Department of Nephrology in the People's Hospital of Nanchuan Chongqing from January 2022 to January 2023 were selected as the study subjects,and this group of patients was used as the training set.Another 50 patients who underwent hemodialysis in the same hospital from February 2023 to February 2024 were selected as the validation set for the study.The general and clinical data of patients were collected and followed up for one year.The risk factors of falls in hemodialysis patients were analyzed,and a nomogram prediction model was constructed.The discrimination and goodness of fit of the model were verified by ROC curve and Hosmer-Lemeshow test.Results According to whether the subjects fell,they were divided into the fall group(n=79)and the control group(n=121),and the incidence of patients falling in the blood purification center of our hospital was 39.5%.Univariate logistic regression analysis showed that age,im-paired vision,use of walking AIDS,diastolic blood pressure before dialysis,potassium,self-care ability score,diabetes,stroke,use of hypoglycemic agents and sleeping pills were all risk factors for falls of hemodialysis pa-tients(P<0.05).Multivariate Logistic regression analysis showed that the use of walking AIDS,potassium(≥4.65 mmol/L),self-care ability score(≤83),stroke and sleeping pills were all independent risk factors for the fall of hemodialysis patients(P<0.05).The area under ROC curve was 0.796,and its sensitivity and speci-ficity were 64.8%and 89.9%respectively.(Hosmer-Lemeshow test:x2=5.041,P=0.283).Conclusion The risk prediction model constructed in this study can effectively predict the risk of falls in hemodialysis patients,and provide evidence for clinical formulation of fall prevention programs.

HemodialysisFallPrediction modelEffectiveness analysisRegression analysis

曾雅琳、李霞、霍洁

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重庆市南川区人民医院肾内科,重庆 408400

血液透析 跌倒 预测模型 效能分析 回归分析

2024

现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
年,卷(期):2024.40(20)