现代医药卫生2024,Vol.40Issue(20) :3502-3506.DOI:10.3969/j.issn.1009-5519.2024.20.016

信迪利单抗联合安罗替尼治疗PD-L1阳性肺肉瘤样癌1例并文献复习

A case of PD-L1-positive pulmonary sarcomatoid carcinoma treated with sindilizumab in combination with anilotinib and literature review

郭迎雪 张婷婷 陈旭 王莹莹 李方华 王远
现代医药卫生2024,Vol.40Issue(20) :3502-3506.DOI:10.3969/j.issn.1009-5519.2024.20.016

信迪利单抗联合安罗替尼治疗PD-L1阳性肺肉瘤样癌1例并文献复习

A case of PD-L1-positive pulmonary sarcomatoid carcinoma treated with sindilizumab in combination with anilotinib and literature review

郭迎雪 1张婷婷 1陈旭 2王莹莹 1李方华 1王远1
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作者信息

  • 1. 胜利油田中心医院,山东 东营 257034
  • 2. 东营市垦利区人民医院,山东 东营 257500
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摘要

该文报道1例78岁男性晚期肺肉瘤样癌患者,PD-L1阳性表达,该患者通过联合使用信迪利单抗和安罗替尼进行治疗,疗效达到部分缓解(PR),无进展生存期(PFS)达到30个月.治疗过程中出现了2级高血压和其他短暂的心脏问题,但整体生活质量良好.

Abstract

This article reports on a 78-year-old male patient with advanced pulmonary sarcomatoid car-cinoma with positive PD-L1 expression,who achieved partial remission(PR)and progression-free survival(PFS)of 30 months with sindilizumab and amilorotinib.Grade 2 hypertension and other transient cardiac problems occurred during treatment,but overall quality of life was good.

关键词

肺肉瘤样癌/信迪利单抗/安罗替尼/免疫治疗/案例报告

Key words

Pulmonary sarcomatoid cancer/Sintilimab/Anlotinib/Immunotherapy/Case rep-ert

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出版年

2024
现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
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