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外阴佩吉特病伴腺癌1例并文献复习

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外阴佩吉特(Paget)病(VPD)是一种极为罕见的妇科恶性肿瘤,因其发病率低及临床症状不典型,故治疗缺乏循证医学证据。该文报道1例VPD伴腺癌的病例,以外阴肿物,伴有瘙痒、疼痛症状为表现,病理活检明确诊断,入院后经妇科肿瘤多学科综合治疗协作组团队行广泛性外阴切除术+双侧腹股沟淋巴结清扫术+肛周病损切除术+带蒂皮瓣移植术,术后愈后良好。该文通过回顾性分析此病例的诊疗过程并结合相关文献,探讨VPD的临床诊治,以期为VPD的诊疗过程提供参考。
Paget's disease of vulva with adenocarcinoma:a case report and literature review
Paget's disease of vulva(VPD),also known as vulvar Paget's disease,is a very rare gyneco-logical malignant tumor,as its incidence is low and the clinical symptoms are not typical,therefore,the treat-ment lacks evidence-based medicine.This paper reports a case of VPD,which presents with vulva swelling,ac-companied by pruritus and pain symptoms,and is diagnosed by pathological biopsy.After admission,the team of Multidisciplinary Comprehensive Treatment of Gynecological Tumors(MDT)performed extensive vulvar excision+bilateral inguinal lymph node dissection+perianal lesion excision+pedicled skin flap transplanta-tion,and the postoperative recovery was good.This paper aims to retrospectively analyze the diagnostic and treatment process of this case and combine relevant literature to discuss the clinical diagnosis and treatment of VPD,in order to provide reference for the diagnosis and treatment of VPD.

Paget's disease of vulvaAdenocarcinomaDiagnosisCase report

王希、张伶俐、陈云、颜乐融

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湖南中医药大学,湖南长沙 410208

湖南中医药高等专科学校附属第一医院/湖南省直中医医院妇科,湖南株洲 412000

湘南学院,湖南郴州 423000

外阴佩吉特病 腺癌 诊断 案例报告

2024

现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
年,卷(期):2024.40(20)