Metabolic associated fatty liver disease is a chronic liver disease associated with obesity,type 2 diabetes and hyperlipidemia.The incidence of metabolic associated fatty liver disease is increasing year by year,which seriously affects the quality of life of patients and brings heavy medical burden to patients and so-ciety.Its pathogenesis involves a variety of factors,such as two-hit and multiple-hit,Helicobacter pylori infec-tion and excessive activation of sympathetic nerves.The treatment methods include changing lifestyle,impro-ving insulin resistance,regulating intestinal flora,and macrophage targeted therapy.This article reviews the progress in the diagnosis and treatment of metabolic associated fatty liver disease.
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