The consistency of high-resolution magnetic resonance for ischemic stroke subtyping in intracranial artery stenosis ischemic stroke patients in China
Objective To compare the consistency of Chinese ischemic stroke subtyping(CISS)in is-chemic stroke(IS)patients with high-resolution magnetic resonance(HRMR)and non-HRMR intracranial artery stenosis among different investigators.Methods A total of 110 patients with intracranial artery steno-sis IS admitted to the Department of Neurology of the Second Affiliated Hospital of Chongqing Medical Uni-versity for hospitalization from January to December 2022 were retrospectively selected,and a total of 97 cases were included according to the inclusion/exclusion criteria,of which 70 cases were male and 27 cases were fe-male;their ages ranged from 27 to 95 years old;and there were 41 cases in the HRMR group and 56 cases in the non-HRMR group.Clinical and imaging data of patients in the two groups were evaluated independently by two investigators,and CISS etiology and pathogenic mechanism typing was performed,and the intragroup correlation coefficient(ICC)method was used to compare the consistency of CISS typing and pathogenic mechanism typing between different investigators.Results For etiologic typing:there were 39 cases of con-cordance and 2 cases of discordance in the HRMR group,with excellent concordance(ICC=0.793,P<0.001);and there were 45 cases of concordance and 11 cases of discordance in the non-HRMR group,with moderate concordance(ICC=0.692,P<0.001).Regarding the typing of pathogenic mechanism of intracrani-al atherosclerotic type of large arteries:there were 31 cases of concordance and 7 cases of discordance among 38 patients in HRMR group,with excellent concordance(ICC=0.751,P<0.001);and there were 23 cases of concordance and 10 cases of discordance among 33 patients in non-HRMR group,with moderate concordance(ICC=0.686,P<0.001).Conclusion HRMR improves consistency in staging the etiology and pathogenic mechanisms of CISS in patients with intracranial arterial stenosis IS from different investigators.
Ischemic strokeChinese ischemic stroke subclassificationIntracranial atherosclerotic stenosisHigh resolution magnetic resonance