Incidence and risk factors for peristomal moisture-associated skin damage:a meta-analysis
Objective To systematically evaluate the incidence and risk factors for peristomal moisture-associated skin damage(PMASD).Methods Databases including CNKI,Wanfang,VIP,EMbase,PubMed,Web of Science,and Cochrane Library were searched for studies on the incidence and influencing factors of PMASD in patients with enterostomy,with a retrieval period up to October 2023.The included studies were analyzed using Stata software for meta-analysis.Results Eleven studies involving 3 222 patients were included.The incidence of PMASD was 41％[95％confidence interval(95％CI)0.30-0.51].A total of 22 risk factors were identified,with 16 being combinable.Age[odds ratio(OR)=1.06,95％CI 1.03-1.09],gender(OR=1.38,95％CI 1.04-1.84),education level(OR=4.17,95％CI 2.27-7.68),patient history of radiotherapy(OR=5.42,95％CI 3.89-7.56),diabetes(OR=3.80,95％CI 1.03-1.09),type of stoma(OR=3.14,95％CI 2.20-4.48),type of ostomy pouch worn(OR=4.46,95％CI 1.95-10.20),stoma com-plications(OR=1.98,95％CI 2.81-3.17),patient self-care ability for stoma(OR=2.65,95％CI 3.41-6.36),stoma height(OR=1.42,95％CI 1.30-1.94),wound in the pouch base area(OR=4.97,95％CI 3.50-7.06),pouch leakage＞3 times(OR=2.97,95％CI 1.59-5.54),surgical approach(OR=2.12,95％CI 1.51-2.97),and weight gain or loss less than 5 kg(OR=1.29,95％CI 1.17-1.42)were all associated with the occurrence of PMASD.Conclusion Existing evidence suggests that the incidence of PMASD is high and there are numerous risk factors contributing to it.Medical staff should conduct early interventions targe-ting these risk factors to mitigate the impact of adverse outcomes on patients.
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