首页|miRNA在妊娠相关疾病中的研究进展

miRNA在妊娠相关疾病中的研究进展

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最近有研究表明,微小RNA(miRNA)在妊娠相关疾病中发挥一定的诊治作用。miRNA是一种小的非编码RNA,可通过结合靶mRNA的3'非翻译区诱导翻译抑制或降解,可能是监测各种疾病的理想生物标志物。因此,探索miRNA对于明确妊娠相关疾病的发病机制及靶向治疗具有重要意义。该文综述了miRNA在妊娠相关疾病中的研究进展,及早发现妊娠相关疾病及其隐匿病情,达到早诊断、早干预的目的,最终改善母儿结局。
Research progress of miRNA in pregnancy-related diseases
Recent studies have shown that microRNA(miRNA)play a role in the diagnosis and treat-ment of pregnancy-related diseases.MiRNA is small non-coding RNA that can induce translation inhibition or degradation by binding to the 3'untranslated region of target mRNA and may be ideal biomarkers for monito-ring various diseases.Therefore,the exploration of these miRNA is of great significance for clarifying the pathogenesis and targeted therapy of pregnancy-related diseases.This article reviews the research progress of miRNA in pregnancy-related diseases,so as to detect pregnancy-related diseases and their hidden diseases early,achieve the purpose of early diagnosis and intervention,and ultimately improve maternal and infant out-comes.

MicroRNAPregnancy-related diseasesDiagnosisTherapyReview

王霞利、何西彦、曲涛、杨青、孙晓彤

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甘肃中医药大学,甘肃 兰州 730000

甘肃省人民医院,甘肃 兰州 730000

微小RNA 妊娠相关疾病 诊断 治疗 综述

2024

现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
年,卷(期):2024.40(23)