Research progress of biomarkers related to prognosis and diagnosis of sepsis
Sepsis is a life-threatening organ dysfunction caused by inflammation disorder caused by in-fection.It is a common disease in intensive care medicine with a high mortality rate.Its incidence is increasing globally,with more than two million cases per year.Early diagnosis of sepsis is essential for timely initiation of appropriate treatment to improve patient outcomes and reduce healthcare costs.Early identification of sepsis in the emergency department is challenging for several reasons,including limited visit times due to overcrow-ding and overlapping symptoms in different clinical conditions.Therefore,there is an urgent need for conven-ient biomarkers with good predictive power to help physicians identify high-risk patients and make treatment decisions.This article reviews the biomarkers related to prognosis and diagnosis of sepsis that are readily a-vailable in clinical practice.