RNA interference (RNAi) refers to the post-transcriptional gene silencing induced by dsRNA or siRNA. The mechanism is that the dsRNA or siRNA was pairing complementarily to the specific sites of the target sequence, which would hinder the transcription of the target se-quence or induce mRNA degradation to inhibit gene expression. RNAi was a high-efficiency, high-specific gene silencing technology, which is not only a important tool in the fundamental re-search, but also widely used in clinical studies in the treatment of cancer, viral diseases and other diseases.
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